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Clinical research behind Living Well.

A clear view of the research behind Living Well: what has been published, what comes from real-world experience, and what is still being explored.

PUBLISHED · PEER REVIEWED

Living Well in women
treated for breast cancer.

A randomized controlled pilot trial in Germany evaluated the Living Well app alongside usual care.

WileyPsycho-Oncology
2024 · Peer reviewed

Studying emotional well-being in breast cancer

70women with breast cancer
12weeks of app use

A randomized, unblinded pilot trial in Germany.

Read the publication

Change in anxiety over 12 weeks

Mean reduction in HADS anxiety score. A larger reduction indicates greater improvement.

Living Well + usual care
32 participants
1.94
Usual care
38 participants
0.53
02.5 points
Heinrich et al., 2024, section 3.2 · Between-group p = 0.014. Group averages do not predict individual results.

What the trial found

AnxietyImprovement observed
Health-related quality of lifeImprovement observed
Illness perceptionImprovement observed
DepressionBenefit not demonstrated
DistressNot statistically significant

Between-group findings at 12 weeks. This is a categorical summary, not a chart of effect sizes.

This is evidence about the Living Well app. It is not a trial of the complete U.S. Prosoma Health navigation and coaching program.

Study details: methods, funding & limitations
Population
70 women with breast cancer
Study groups
32 intervention / 38 control
Intervention
Living Well plus usual care
Comparator
Usual care alone
Publication
Wiley · Psycho-Oncology, October 2024
Study setting
Germany

How the results were analyzed

The anxiety results use an intention-to-treat analysis with last observation carried forward. The between-group comparison at 12 weeks had p = 0.014.

Study scope and funding

This was a small, unblinded pilot trial in women with breast cancer. Findings should not be generalized to every person affected by cancer. The study was funded by Prosoma GmbH; author employment and consultancy relationships were disclosed.

Read the Wiley publication

Heinrich et al. (2024). Effects of Mobile Application-Based Cognitive Behavioral Therapy on Psychological Outcomes in Women Treated for Breast Cancer. DOI: 10.1002/pon.70003.

OBSERVATIONAL RESEARCH

Real-world experience with Living Well.

Prosoma’s research portfolio includes real-world analyses involving people using Living Well, including users supported through Techniker Krankenkasse in Germany.

These observational analyses explore app engagement, symptom changes, and patient experience.

Engagement and reported improvement

Percentage meeting the report’s criteria for clinically significant improvement.

Fewer than 10 lessons (n = 265)At least 10 lessons (n = 238)

Anxiety

Fewer than 10
28%
At least 10
34%

Depression

Fewer than 10
22%
At least 10
32%
0%100%
Prosoma, Users Engagement: Real World Data Analysis, July 2023. Observational, not randomized or peer reviewed. These results do not show that completing more lessons caused improvement.
Study details: source, population & limitations

Who was included

The analysis included selected app users with at least two optional assessment scores. It compared fewer than 10 lessons (265 users) with at least 10 lessons (238 users).

How to interpret the comparison

Selection, missing data, and differences between users may affect the results. The reports cover different populations, baseline symptom levels, and analysis sets. International results do not automatically describe U.S. outcomes.

Source

Prosoma, Users Engagement: Real World Data Analysis, July 2023, improvement table. The percentages use the report’s criteria for clinically significant improvement.

Scientific reports and conference presentations.

Alongside the peer-reviewed publication, the research collection includes conference presentations, preliminary reports, and white papers. These sources have different levels of review and answer different questions.

Conference presentations

The 2025 WCP poster explores serious micro-games. The 2025 Würzburg presentation examines illness perception and psychological outcomes. These are conference materials, not additional journal publications.

Clinical short reports

The research collection includes a Polish randomized trial report. The 2026 PROs and PROMs report presents preliminary findings. Journal publication has not been verified for these reports.

Engagement and medical reports

The 2023 user engagement analysis and 2024 CSS annual medical report add context on app use and research progress. They should be read with their own methods and reporting periods.

Economic white papers

The DACH and TK materials explore modeled economics. Their estimates depend on assumptions and do not establish measured U.S. savings.

RESEARCH IN DEVELOPMENT

Ongoing research.

Prosoma’s research portfolio spans clinical trials, observational analyses, and work with healthcare organizations. Each study addresses a defined population and research question.

The library distinguishes published findings from preliminary reports and research still in development.

READING THE EVIDENCE

Understanding the evidence and its limits.

Published clinical studies

Describe a defined intervention, population, comparator, and set of outcomes.

Real-world observations

Describe experience outside a controlled trial, with limitations such as selection and missing data.

Economic models

Estimate possible costs or savings using assumptions. They are not measured savings or a guaranteed return.

Proposed outcomes

Identify questions to evaluate in future partnerships. They are not established results.

Current research does not establish Prosoma-specific reductions in emergency visits, readmissions, or total U.S. care costs. No claims of superior outcomes are made here.

Questions about the research?

Our team can help you understand the evidence behind Living Well and how it relates to the support you’re exploring.

Talk to our teamFor partnership enquiries

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